Atopic dermatitis (eczema) - Symptoms and causes (2024)

Overview

Atopic dermatitis behind the knees

Atopic dermatitis (eczema) - Symptoms and causes (1)

Atopic dermatitis behind the knees

Atopic dermatitis can cause a very itchy rash. Atopic dermatitis most often occurs where the skin flexes — inside the elbows, behind the knees and in front of the neck.

Atopic dermatitis (eczema) is a condition that causes dry, itchy and inflamed skin. It's common in young children but can occur at any age. Atopic dermatitis is long lasting (chronic) and tends to flare sometimes. It can be irritating but it's not contagious.

People with atopic dermatitis are at risk of developing food allergies, hay fever and asthma.

Moisturizing regularly and following other skin care habits can relieve itching and prevent new outbreaks (flares). Treatment may also include medicated ointments or creams.

Symptoms

Atopic dermatitis on the chest

Atopic dermatitis (eczema) - Symptoms and causes (2)

Atopic dermatitis on the chest

Inflammation caused by atopic dermatitis can cover large areas of the body, such as the chest, or be limited to a few small spots.

Infantile eczema

Atopic dermatitis (eczema) - Symptoms and causes (3)

Infantile eczema

Atopic dermatitis in infants (infantile eczema) appears here as red, itchy patches on very dry skin.

Atopic dermatitis (eczema) symptoms can appear anywhere on the body and vary widely from person to person. They may include:

  • Dry, cracked skin
  • Itchiness (pruritus)
  • Rash on swollen skin that varies in color depending on your skin color
  • Small, raised bumps, on brown or Black skin
  • Oozing and crusting
  • Thickened skin
  • Darkening of the skin around the eyes
  • Raw, sensitive skin from scratching

Atopic dermatitis often begins before age 5 and may continue into the teen and adult years. For some people, it flares and then clears up for a time, even for several years.

When to see a doctor

Talk with a health care provider if you or your child:

  • Has symptoms of atopic dermatitis
  • Is so uncomfortable that the condition is affecting sleep and daily activities
  • Has a skin infection — look for new streaks, pus, yellow scabs
  • Has symptoms even after trying self-care steps

Seek immediate medical attention if you or your child has a fever and the rash looks infected.

More Information

  • Mayo Clinic Minute: Eczema occurs in people of all ages

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Causes

Mayo Clinic Minute: Eczema occurs in people of all ages

Jason T. Howland: Atopic dermatitis is a sensitivity disease of the skin, similar to asthma in the lungs, hay fever in the sinuses and food allergies in the gut.

Dawn Marie R. Davis, M.D.: It's a multisystem disorder. Inflammation affects the skin, and the skin is more sensitive than usual.

Howland: It's a chronic condition and tends to flare periodically. The symptoms vary.

Dr. Davis: Atopic dermatitis tends to be red, weepy, crusty, itchy, flaky patches, like oval or circular-shaped areas on the skin.

Our skin is like a brick wall. And over time as we age, or genetically if we are predisposed to sensitive skin, it can look like a wicker basket more than a brick wall.

Howland: Adult eczema often occurs in patches on areas of the body prone to friction or sweat.

Dr. Davis: Where your waistband would sit, where your socks or shoes would rub. If you have a watch, where you would wear your watch. If you have a headband or certain things that you wear along your neck, like a necklace or a tie.

It's important to bathe regularly. It's important to hydrate the skin with a moisturizer that is hypoallergenic. It's important to monitor for infection.

Howland: If those self-care steps don't help, your dermatologist may prescribe topical or oral medications, or other therapies.

For Mayo Clinic News Network, I'm Jason Howland.

In some people, atopic dermatitis is related to a gene variation that affects the skin's ability to provide protection. With a weak barrier function, the skin is less able to retain moisture and protect against bacteria, irritants, allergens and environmental factors — such as tobacco smoke.

In other people, atopic dermatitis is caused by too much of the bacteria Staphylococcus aureus on the skin. This displaces helpful bacteria and disrupts the skin's barrier function.

A weak skin barrier function might also trigger an immune system response that causes the inflamed skin and other symptoms.

Atopic dermatitis (eczema) is one of several types of dermatitis. Other common types are contact dermatitis and seborrheic dermatitis (dandruff). Dermatitis isn't contagious.

Risk factors

The main risk factor for atopic dermatitis is having had eczema, allergies, hay fever or asthma in the past. Having family members with these conditions also increases your risk.

Complications

Complications of atopic dermatitis (eczema) may include:

  • Asthma and hay fever. Many people with atopic dermatitis develop asthma and hay fever. This can happen before or after developing atopic dermatitis.
  • Food allergies. People with atopic dermatitis often develop food allergies. One of the main symptoms of this condition is hives (urticaria).
  • Chronic itchy, scaly skin. A skin condition called neurodermatitis (lichen simplex chronicus) starts with a patch of itchy skin. You scratch the area, which provides only temporary relief. Scratching actually makes the skin itchier because it activates the nerve fibers in your skin. Over time, you may scratch out of habit. This condition can cause the affected skin to become discolored, thick and leathery.
  • Patches of skin that's darker or lighter than the surrounding area. This complication after the rash has healed is called post-inflammatory hyperpigmentation or hypopigmentation. It's more common in people with brown or Black skin. It might take several months for the discoloration to fade.
  • Skin infections. Repeated scratching that breaks the skin can cause open sores and cracks. These increase the risk of infection from bacteria and viruses. These skin infections can spread and become life-threatening.
  • Irritant hand dermatitis. This especially affects people whose hands are often wet and exposed to harsh soaps, detergents and disinfectant at work.
  • Allergic contact dermatitis. This condition is common in people with atopic dermatitis. Allergic contact dermatitis is an itchy rash caused by touching substances you're allergic to. The color of the rash varies depending on your skin color.
  • Sleep problems. The itchiness of atopic dermatitis can interfere with sleep.
  • Mental health conditions. Atopic dermatitis is associated with depression and anxiety. This may be related to the constant itching and sleep problems common among people with atopic dermatitis.

Prevention

Developing a basic skin care routine may help prevent eczema flares. The following tips may help reduce the drying effects of bathing:

  • Moisturize your skin at least twice a day. Creams, ointments, shea butter and lotions seal in moisture. Choose a product or products that work well for you. Ideally, the best one for you will be safe, effective, affordable and unscented.

    Using petroleum jelly on your baby's skin may help prevent development of atopic dermatitis.

  • Take a daily bath or shower. Use warm, rather than hot, water and limit your bath or shower to about 10 minutes.
  • Use a gentle, nonsoap cleanser. Choose a cleanser that's free of dyes, alcohols and fragrance. For young children, you usually need only warm water to get them clean — no soap or bubble bath needed. Soap can be especially irritating to the skin of young children. For people of any age, deodorant soaps and antibacterial soaps can remove too much of the skin's natural oils and dry the skin. Don't scrub the skin with a washcloth or loofah.
  • Pat dry. After bathing, gently pat the skin with a soft towel. Apply moisturizer while your skin is still damp (within three minutes).

The triggers for atopic dermatitis vary widely from person to person. Try to identify and avoid irritants that trigger your eczema. In general, avoid anything that causes an itch because scratching often triggers a flare.

Common triggers for atopic dermatitis include:

  • Rough wool fabric
  • Dry skin
  • Skin infection
  • Heat and sweat
  • Stress
  • Cleaning products
  • Dust mites and pet dander
  • Mold
  • Pollen
  • Smoke from tobacco
  • Cold and dry air
  • Fragrances
  • Other irritating chemicals

Infants and children may have flares triggered by eating certain foods, such as eggs and cow's milk. Talk with your child's health care provider about identifying potential food allergies.

Once you understand what triggers your eczema, talk with your health care provider about how to manage your symptoms and prevent flares.

By Mayo Clinic Staff

Atopic dermatitis (eczema) - Symptoms and causes (2024)
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